SKU: 43378377808

Nucleoskin Topic 5x3ml Promoitalia

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Description

Nucleoskin Topic 5x3ml PromoitaliaPromoitalia NUCLEOSKIN TOPIC Use by date 03 2024 Promoitalia NUCLEOSKIN TOPIC the power of PDRN Polynucleotides combined with the efficacy of Hyaluronic Acid. The new products that contain highly purified Polynucleotidic matrices are able to activate processes of skin bio regeneration both at the deep level (adipose and bone tissue), and at the level of dermis (fibroblastic stimulation). BENEFITS: Skin lifting effect Biorestructuring of the deep

Promoitalia NUCLEOSKIN TOPIC

Use by date 03/2024

Promoitalia NUCLEOSKIN TOPIC – the power of  PDRN – Polynucleotides combined with the efficacy of Hyaluronic Acid.

The new products that contain highly purified Polynucleotidic matrices are able to activate processes of skin bio-regeneration both at the deep level (adipose and bone tissue), and at the level of dermis (fibroblastic stimulation).

BENEFITS:

  • Skin lifting effect
  • Biorestructuring of the deep dermis
  • Moisturizing action
  • Improve the look of small depressed scars and of periocular wrinkles
  • Highly indicated pre-and post-surgical treatments (Blepharoplasty, lifting, resurfacing laser
  • Liquid lifting
    PDRNs work by stimulating rejuvenation processes and toning tissues.
  • Filler effect
    Hyaluronic acid reduces the appearance of skin blemishes such as wrinkles and skin depressions.
  • Antioxidant
    Glutathione defends the skin from free radicals’ attack and restores the correct amount of acetyl cysteine for proper cellular defence.

Application technique and protocol

  • Nucleoskin can be applied using either the dermapen or a dermaroller.
  • The intensity of the treatment, the depth of the needles, must be calibrated according to the type of skin and the characteristics of the patient.
  • The application through Hyaluron Pen is also indicated, in this case we do not recommend treatment in the vermilion area.
  • 1-2 ml of product are usually required to treat the facial area.
  • The treatment must be repeated every 20-25 days for a minimum of 4 sessions.

Protocol for face and body

  • Normally we need 1.5 ml for face, using 0.025 ml of product for each application (about 60 micro applications for the whole face).
  • For body the quantities are necessarily higher: 3ml for each session with 0.1 ml per application.
  • We recommend 4/6 session, one every 20 days.

Protocol for periocular area

  • The periocular area is much more delicate and for this reason the product must be diluted with physiological solution with ratio 1:1 (1 ml of product + 1 ml of physiological solution). In this case we need about 0,025 ml for single application.
  • We recommend 3/4 session, one every 28 days.

KEY INGREDIENTS:

  • Biologically-derived PDRN with high molecular weight (2500KD) 2%
  • Hyaluronic Acid 10 mg/ml crosslinked with BDDE
  • Glutathione 2 mg/ml

Polynucleotides (PDRN) – Polydeoxyribonucleotides, or PDRNs, are the molecules that make up our DNA, our genetic code, which is why they are very precious molecules for the body and cells. Stimulates cellular receptors and the maturation of fibroblasts in myofibroblasts.

Their main feature, in addition to transmitting genetic information, is that of being able to activate many cells membrane receptors and trigger biological processes that are fundamental for the life of the cells themselves.

Hyaluronic acid – is a molecule naturally present in our body and is produced by fibroblast, cells that have the aim of moisturizing the tissue, giving them firmness and plasticity. Hyaluronic acid absorbs water, retains, and releases it according to the needs of the body and, therefore, maintains the right hydration and moisture of the tissues.

Glutathione – is an antioxidant found in plants, animals, fungi, and in some bacteria. It can prevent damage of important cellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides, and heavy metals. It may also affect skin pigmentation by inhibiting tyrosinase activity during melanogenesis, either directly or indirectly.

Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 43378377808

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henry c.
West Palm Beach, US
★★★★★ 5
It's Pittsburgh Steelers!!
Style: Goal Post Chew Toy, Color: PITTSBURGH STEELERS
I ordered it for our "Grandpups"! My daughter says it's tuff & strong but at the same time it gives enough for the dogs to bite down on it. They love it!! I ordered it along with a few Steeler bandanas!
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Reviewed in the United States on March 15, 2026
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MizC72
Port Orchard, US
★★★★★ 3
Not for the serious chewers
Style: Goal Post Chew Toy, Color: NEW ENGLAND PATRIOTS
Great novelty dog toy but if your dog is a real chewer like my Frenchie is, he had this turned this into a weapon in a matter of a week. The chewed up plastic was super sharp! But other than that, Go Pats!
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Reviewed in the United States on October 9, 2025
S
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Sierra Thomas
Omaha, US
★★★★★ 5
Buy it!!
Style: Goal Post Chew Toy, Color: Dallas Cowboys
It quickly became my guy's dog's favorite toy. Sturdy, cute, and affordable. I ordered another one
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Reviewed in the United States on January 5, 2026
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Echo Kennedy
Birmingham, US
★★★★★ 4
My puppy loves this chew toy.
Style: Goal Post Chew Toy, Color: Detroit Lions
It’s one of his favorite toys to show off and chew. I constantly find him carrying it around. The only downside is that the Lions emblem wore off really quickly. It’s still a super cool toy though.
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Reviewed in the United States on January 13, 2025
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Herrera Jenessys
West Palm Beach, US
★★★★★ 5
Heavy nylon. No squishy or chewable for pups.
Style: Goal Post Chew Toy, Color: PHILADELPHIA EAGLES, Style: Goal Post Chew Toy, Color: PHILADELPHIA EAGLES
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Reviewed in the United States on November 8, 2025

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