SKU: 79882672697

Renue Blue Face Serum

Sale price$64.80 Regular price$72.00
Save 10%

Pay in installments of $18.00 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Aug 1 - Aug 6

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

Renue Blue Face SerumRenue Blue Face & Hand Serum Renue Blue Face & Hand Serum works at the cellular level to deliver time released actives that restore NAD to improve skin's texture, firmness, and dermal matrix. The epitome of science and performance, Renue Blue Face & Hand Serum works renews cells from within using a proprietary Liposomal Methylene Blue with NAD Complex (NAD+, NMN, and NR)science backed nutrients that provide nourishment on the cellular level. Renue

Renue Blue  Face & Hand Serum

Renue Blue Face & Hand Serum works at the cellular level to deliver time released actives that restore NAD⁺ to improve skin's texture, firmness, and dermal matrix.

The epitome of science and performance, Renue Blue Face & Hand Serum works renews cells from within using a proprietary Liposomal Methylene Blue with NAD⁺ Complex (NAD+, NMN, and NR)science-backed nutrients that provide nourishment on the cellular level.

Renue Blue works at the cellular level to deliver time-released actives that restore NAD⁺ to improve skin's texture, firmness, and dermal matrix.

Nano-sized liposomes penetrate quickly and deeply into dermal layers to deliver a very high concentration of active ingredients that provide unique therapeutic benefits over all other serums.

Expertly formulated with liposomal NAD⁺ Complex (NAD+, NMN, and NR) and Methylene Blue, along with Apocynin, and Glutathione, this potent delivery system offers a deeper penetration of key ingredients into the skin's surface to combat the most visible signs of aging and promote vibrant, youthful-looking skin.

Use day and night with Renue Blue Face Creme. Suitable for all skin types.

METHYLENE BLUE

Methylene Blue has been studied for a wide range of ailments, many of which are aging-related illnesses, and there are currently over 20,000 studies on Pubmed. One study conducted at the University of Maryland tested the potential dermal anti-aging benefits of four antioxidants, one of which was Methylene Blue.

Among all of the antioxidants studied, Methylene Blue was by far, the most effective.


University of Maryland Study


The study was conducted by the Department of Cell Biology & Molecular Genetics, at the University of Maryland.

In the study, researchers tested out four antioxidants on the skin, one of which was Methylene Blue. The second one was N. Acetyl Cysteine, or NAC, a very popular antioxidant, often taken as a supplement. The last two were MitoQ and mTEM - both of which are mitochondrial targeting antioxidants.

They applied each one topically to skin fibroblasts of healthy middle-aged adults, adults 80 and older and from people with progeria.

For most studies, skin fibroblasts are obtained through a non-invasive procedure that involves numbing at the site and taking a punch skin biopsy sample.

Progeria is an extremely rare genetic condition characterized by dramatic and rapid aging. It causes severe hardening of the arteries at a young age, and often those afflicted don't live past their teenage years.

Some researchers believe that Progeria may hold the key to understanding the precise causes of aging - so that it can be slowed down.

For this study, the Progeria fibroblasts were used as an accelerated model for normal aging - because they share many of the features in common with normal aging.

One part of the study looked at the effectiveness of these antioxidants to decrease oxidative stress. Oxidative stress plays a major role in the aging process in the skin, much of which is driven by UV exposure.

Among all of the antioxidants studied, Methylene Blue was the most effective.

It reduced mitochondrial reactive oxygen species, and promoted skin cell proliferation - which involves an increase in the cell division rate and that leads to a higher number of new, healthy cells created during cell turn-over.

The normal skin and the progeria skin treated with the Methylene Blue, showed much higher skin proliferation levels.

Research shows that as a person ages, proliferation of cells in the basal (or deepest) layer reduces. The epidermis (or the outer layer) then becomes thinner. The nutrition supply to the outer layer then weakens because of dysfunction in the deeper layers.

This process of decreased proliferation in the skin, is associated with senescence. Senescent cells, also known as zombie cells, can cause a lot of damage. They are cells that eventually stop multiplying, yet they don't die off like they should. Instead, they remain in the body and continue to release damaging chemicals that trigger inflammation.

In the second part of the study, cellular senescence was examined.

Different fibroblasts were used and treated with Methylene Blue. Two fibroblasts from people over 80 were used and two fibroblasts from people under 30 were used.

The over 80 fibroblasts showed increases in biomarkers of senescence. When treated with Methylene Blue, there was a reduction in cellular senescence, especially notable for the older skin fibroblasts. This showed that Methylene Blue is effective at reducing cellular senescence.

The study revealed that skin treated with Methylene Blue had an increase in skin thickness and improved levels of skin hydration.

This is important because skin thickness and loss of hydration are issues of aging skin. Dermal thickness decreases by about 6% every decade.

Source: Anti-Aging Potentials of Methylene Blue for Human Skin Longevity

Among all of the antioxidants studied, Methylene Blue was the most effective.

The Methylene Blue-treated skin showed a greater reduction in DNA damage, leading to cell rejuvenation.

There was an increase the cell division rate, leading to a higher number of healthy new cells created during cellular turnover.

In addition, there was less senescence - and a slower rate of cell death, indicating that skin cells became healthier and lived longer.

There was also improved hydration levels and dermal thickness was increased.

Study: Anti-Aging Potentials of Methylene Blue for Human Skin Longevity https://www.nature.com/articles/s41598-017-02419-3

Fighting against Skin Aging The Way from Bench to Bedside https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047276/

The evolving role of the NAD+/nicotinamide metabolome in skin homeostasis, cellular bioenergetics, and aging https://sci-hub.do/10.1016/j.dnarep.2014.04.005

NAD in Skin: Therapeutic Approaches for Niacin https://sci-hub.do/10.2174/138161209787185760

Characteristics of the Aging Skin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840548/

Xiong, ZM, O’Donovan, M., Sun, L., et al. Anti-Aging Potentials of Methylene Blue for Human Skin Longevity. Sci Rep 7, 2475 (2017) (https://doi.org/10.1038/s41598-017-02419-3). Licensed under CC-BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Disclaimer – Neither the license nor link to the foregoing publication constitutes or implies any sponsorship or affiliation with, or endorsement or approval of Renue By Science by the authors.


RENUE™ - 2 Step Skin Rejuvenation Protocol


 

What's the ideal pH for skin-care products?

You want to look for skin-care products with a pH of 5.5. If anything, they could be as low as 4.5 and as high as 7. The general rule is slightly acidic is preferred for the best complexion.

What pH are Renue™ Products?

Renue™ NAD+ Skincare products are on the optimal 5.5 mark on the pH scale.

High pH (8 to 14)

Skin-care products with a high pH level (also known as alkaline) pose the biggest threat to your skin's pH and acid mantle. That tight, squeaky-clean feeling you might experience after washing your face is the truest sign of cleansers with a high pH and damaged skin barrier. They, as well as other alkaline skin-care products, tend to strip away sebum and natural oils.

Low pH (1 to 6)

Because products with a low pH are at a level closer to skin's natural pH, they will more effectively work with your skin and help cell turnover gently. They're more likely to keep skin bright and smooth, instead of flaky and angry.

However, certain products can be too low of a pH for skin and irritate it. At-home peels and other acid-spiked products tend to have a lower pH level, making them great exfoliants but just as stripping as products with a high pH.

 

These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 79882672697

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.1 ★★★★★
Based on 29 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
W
Verified Purchase
Winter Soldier
Whiting, US
★★★★★ 5
Good book
Format: Paperback
I didn't even play The tie in video game. It's just a good book.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 19, 2023
K
Verified Purchase
Kindle Customer
Bozeman, US
★★★★★ 5
Like
Format: Kindle
I enjoyed it Why? It tells a story of a Jewish master who lost her way and was found...by a lost padawan
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 20, 2021
J
Verified Purchase
John Jaeger
Belleville, US
★★★★★ 4
A prequel to Jedi Fallen Order
Format: Kindle
It’s an interesting read to see Cere Junda and her master Eno Cordova trying to find secrets in hidden temple while tension builds between two civilizations. A typical story about outsiders involved between two societies battling share one land, while trying to find a balance, what have you, it’s not bad and I did like what they we’re going with, it’s just been done before. All in all, a decent story in a galaxy far, far away.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 15, 2021
A
Amazon Customer
Cuba, US
★★★★★ 5
To every Jedi
Format: Kindle
How can I not like anything Jedi and Star Wars. I thought this was an amazing read and it just deepens my love of the Jedi order and the Star Wars universe.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 30, 2023
B
Ben Brown
Carnegie, US
★★★★★ 3
Another "fine" videogame tie-in.
Format: Paperback
“Star Wars: Jedi Fallen Order - Dark Temple” (wow, that’s a mouthful of a title) is the requisite comic book tie-in to the “Star Wars: Jedi: Fallen Order” videogame that was released last month, to which this serves as a prequel. And, like most of Marvel’s “Star Wars” output, it falls squarely into the category of being“perfectly adequate” – the story is diverting enough, without ever being truly gripping, and the characters have just enough personality and quirk to disguise the fact that they’re basically just engines to keep the story moving. Really, the only thing about “Dark Temple” that rises above the level of 'competent' is the art by Paolo Villanelli, which mixes dichotomous colors with sharp line work to meld into something that’s genuinely striking and distinct. Fans of “Fallen Order” might be apt to see what some of their favorite characters were up in the years preceding the game’s story, but rest assured: story-wise, there’s not much to glean here, outside of one or two teasing allusions. Die-hard fans of “Star Wars” will probably enjoy this well enough; anyone else probably need not read.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 16, 2020

recommand products