SKU: 8807072931

Designs for Health - ProbioSpore 60caps

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Description

Designs for Health - ProbioSpore 60capsSupport gastrointestinal health with Probiospore Contains 4 billion CFU of Bacillus coagulans (IS2) per capsule Improves bowel regularity Maintains intestinal good flora Vegan friendly Education: Designs for Health ProbioSpore is a unique spore based probiotic containing Bacillus coagulans (UNIQUE IS 2TM) as a single ingredient. Originally named Lactobacillus sporogenes, Bacillus coagulans is a transient, gram positive, lactic acid producing bacteria

  • Support gastrointestinal health with Probiospore
  • Contains 4 billion CFU of Bacillus coagulans (IS2) per capsule
  • Improves bowel regularity
  • Maintains intestinal good flora
  • Vegan friendly

 

Education:

Designs for Health ProbioSpore is a unique spore-based probiotic containing Bacillus coagulans (UNIQUE IS-2TM) as a single ingredient.

Originally named Lactobacillus sporogenes, Bacillus coagulans is a transient, gram-positive, lactic acid-producing bacteria that is protected from stomach acid by a protein-based spore coating. Instead of dying off as a result of coming into contact with stomach acid, the spore coating expands, and B. coagulans begins to germinate as it moves out of the stomach and into the duodenum where the environment is more amenable. Germination occurs between 4-6 hours after ingestion, and around 85-93% of the ingested and germinated probiotic ends up in the intestines. Further to this, its preferred growth temperature is between 35-50°C.  As a result, B. coagulans displays an excellent stability profile at ambient temperatures

Once germination has taken place, B. coagulans proliferates in the distal parts of the small intestine and is able to produce the isomeric form of lactic acid. The isomeric form is unlikely to give rise to metabolic acidosis.

Being a transient and not a colonising probiotic, B. coagulans does not remain in the intestinal tract for long and begins to be excreted via the faeces around seven days after supplementation ceases. Despite such a short period of time of activity in the bowel, B. coagulans affects the microbial colony in that it helps to regulate beneficial flora and inhibit the proliferation of opportunistic bacteria via the production of “bacteriocin-like substances” and short-chain fatty acids (SCFAs). These compounds support the health of the GI lining and provide direct antagonism to microbial pathogens.

Bacillus coagulans and Digestion

B. coagulans is also able to produce several enzymes that assist digestive processes such as nutrient breakdown and absorption. Some of these enzymes include lipase, protease, α-amylase and both α- & β-galactosidase and assist with protein and carbohydrate digestion.2 Absorption is also facilitated as B. coagulans can reduce inflammation of the gut lining and promote the health of the permeable areas of the microvilli.

Bowel Regularity

As well as digestion, B. coagulans has also been found to assist excretion. It produces metabolites such as diacetyl, SCFAs and vitamins, stimulates peristalsis, reduces amine production, reduces bowel transit time, and improves the overall health of the bowel. This in turn helps to improve bowel regularity and reduce toxin build-up.

A randomised, double-blind, placebo-controlled clinical trial performed using the Unique IS-2TM strain on 100 men and women suffering from functional constipation showed that supplementation with B. coagulans at a dose of 2bn CFU daily improved stool frequency, consistency, pain associated with defecation, and feelings of incomplete evacuation.

Pain associated with Irritable Bowel Syndrome

The specific strain Unique IS-2TM has also been the subject of a clinical trial included in a meta-analysis for its effects on medically diagnosed irritable bowel syndrome.

Daily dosing of 2 billion CFU of Unique IS-2TM daily was studied in a randomised, double-blind, placebo-controlled trial involving 108 men and women fulfilling ROME III criteria for irritable bowel syndrome. Reduction of abdominal pain and an increase in spontaneous complete bowel movements were the primary endpoints studied. Bacillus coagulans Unique IS-2TM was able to show more than a 50% pain reduction score in 90.5% of patients, and significantly reduced the total symptom severity score (including symptoms such as bloating, incomplete evacuation, urgency, straining, passage of gas, bowel habit satisfaction and stool consistency) from 26.7 to 10.6 (placebo 26.7 to 21.5) over the course of eight weeks

A meta-analysis picked up this trial as well as 41 others done on a number of different probiotic species and concluded that Bacillus coagulans Unique IS-2TM is able to effectively reduce abdominal pain associated with medical diagnosed irritable bowel syndrome

 

Directions for use

Adults: Take one capsule daily with water or as directed by your health professional.

Prescribing Information: Bacillus coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate the administration of antibiotics and B. coagulans preparations by at least two hours

Allergen Information

  • No added: Gluten, Dairy, Egg, Sesame, Peanuts and Tree Nuts
  • Free From: Artificial Flavours, Artificial Colours, Sulfites,
  • Contains soybean products
  • Vegan Friendly
Pack: 60 Capsules
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SKU: 8807072931

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Flipflop
West Palm Beach, US
★★★★★ 5
A Special Education Treasure
Format: Board book
I bought this book with one student in mind. A third grade autistic, non verbal, girl with a love for books, animals and reflective surfaces (windows, puddles, utensils and mirrors to name a few). The bright, cheerful illustration was the immediate interest upon her first look. The engaging fun story kept her attention. The last page captivated her. What a complete joy to watch! She will now say "Wiggle" when she wants this book - several times a day. She follows along with her finger while I read. I do not read the last page. She does that all ON HER OWN! Did I mention non verbal?! I'm purchasing another as a Christmas surprise for her to have at home. I highly recommend this book as a fixture in the classroom for Special Education and Early Learning.
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Reviewed in the United States on November 12, 2023
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Amazon Customer
Boise, US
★★★★★ 5
A staple for your Early Education libraries!
Format: Board book, Format: Board book
This book is adorable! One to use at every circle time in my classroom and my at-home children's library. I love the simplicity of the book and the beautiful art throughout. As a special education teacher and caretaker for more typical peers, you need to go in fast and animated to keep the attention of young learners...This book does all of those things and more. The ending with the mirror will teach early prediction skills and allow your child to see themselves as the wiggliest of all! (I chose this book for ages pre-birth through six years old).
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Reviewed in the United States on October 4, 2023
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Gloria A Santa Anna
Birmingham, US
★★★★★ 5
Spoiler Alert! You are Wiggly
Format: Board book
Soooooooo funny! My grandson never stops,, go go go…. So to see at the end the picture is YOU! lol. And the bonus, you go through the animal kingdom associating the animal with how they move…. Instead of sound. Stimulates a different awareness.
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Reviewed in the United States on January 31, 2026
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Genevieve
Whiting, US
★★★★★ 5
Very cute story. Absolutely loved
Format: Board book
This is a great book. Looking forward to many additional ones by the author.
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Reviewed in the United States on December 8, 2024
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Cheryl Dyer
Belleville, US
★★★★★ 5
Playful and FUN -- makes a great holiday gift
Format: Board book
"Are You Wiggly?" is not just a story; it's an adventure that brings laughter, curiosity, and joy to every page. Children learn about various animal movements plus enjoy a fun little surprise at the end. The playful illustrations add to the fun as well! I got several and will be giving as gifts this holiday season.
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Reviewed in the United States on October 12, 2023

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