SKU: 5618214298

PerCP Mouse Anti-Human CD8 Antibody (S-R533)

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Description

PerCP Mouse Anti-Human CD8 Antibody (S-R533)Product Specification Host Mouse Antigen CD8 Synonyms T cell surface glycoprotein CD8 alpha chain; T lymphocyte differentiation antigen T8 Leu 2; MAL; CD8A Location Cell membrane Accession P01732 Clone Number S R533 Antibody Type Mouse mAb Isotype IgG1 Application FCM Reactivity Hu Positive Sample human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation PerCP Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300

Product Specification


Host Mouse
Antigen CD8α
Synonyms T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; MAL; CD8A
Location Cell membrane
Accession P01732
Clone Number S-R533
Antibody Type Mouse mAb
Isotype IgG1
Application FCM
Reactivity Hu
Positive Sample human PBMC
Purification Protein G
Concentration 0.2 mg/ml
Conjugation PerCP
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1.25μl per million cells in 100μl volume Hu

Background

CD8α is a crucial immune glycoprotein that plays a vital role in the immune response by serving as a co-receptor for the T-cell receptor (TCR) on cytotoxic T cells. It forms either a homodimer (α/α) or a heterodimer with CD8β (α/β) to interact with MHC class I molecules on antigen-presenting cells (APCs), facilitating the recognition of intracellular pathogens such as viruses. CD8α also recruits the LCK kinase, which initiates downstream signaling pathways essential for T-cell activation and proliferation. This molecule is critical for the function of cytotoxic T lymphocytes (CTLs) and is involved in various immune-related diseases, including immunodeficiencies and autoimmune conditions.

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SKU: 5618214298

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4.8 ★★★★★
Based on 24 reviews
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Chingyuan
Draper, US
★★★★★ 5
Highly recommended!
Format: Hardcover
I first saw this book at a relative’s house and was immediately drawn in by its content. There’s no text at all, yet it captures children’s interest so strongly—especially when learning the concept of numbers. The illustrations are also beautiful. When my child didn’t yet understand numbers, it was still fun to recognize the animals or see what the characters in the pictures were doing. I really love this book.
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Reviewed in the United States on September 14, 2025
K
Verified Purchase
KB
Pawtucket, US
★★★★★ 5
A Multi-faceted, beautiful book for babies through primary grades.
Format: Hardcover
Our second generation is now loving this beautiful, clever, playful book. Although there are no words, the story line is a delight. A watercolored village develops one page to the next starting with 0 and ending with 12. The pictures add one item in each category for each new number, building on the previous scene. Readers can find and count buildings, children, adults, pine trees, cherry trees, and an assortment of animals. In addition, in a lovely subtle manner, the four northern hemisphere seasons pass from January to December. The details of adult and child activities through time and seasons can be noted. Anno's creativity in this genre is unsurpassed. For my children, and now for my grandson, this book evokes fascination on several levels both aesthetic and intellectual. Start using it as a baby word book, and it will last as a joy throughout early childhood. Not every baby book must be a board book. Teaching children to turn pages gently is easy to do and adds to the amazing, shared experience.
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Reviewed in the United States on February 22, 2015
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Verified Purchase
Chopper
Carnegie, US
★★★★★ 5
Gorgeous book!
Format: Hardcover
Read this over and over with my own children and they loved it. Buying for friends' children/grandchildren and they are loving it, too. Timeless, lots to capture kids' interest and counting. The suggested age is 3 and up, but we used it earlier than 3 years of age; it depends on the child. We're buying them now for newborns figuring they'll "grow into it."
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Reviewed in the United States on September 16, 2021
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Verified Purchase
Dan
San Leandro, US
★★★★★ 4
A truly original concept picture book. Unlike most counting ...
Format: Hardcover
A truly original concept picture book. Unlike most counting concept books that only show one item type (like 2 balls on the page about 2) this book has many items to count on each number page (3 trees, 3 trains, 3 cows, etc, on the pages about the number 3). You have to search around to find each of the items because the author moves the items around each time. :) Yes, it's not as flashy, but it's got what really counts!
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Reviewed in the United States on December 3, 2016
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Verified Purchase
Elisa's Mom
Omaha, US
★★★★★ 5
Excellent early math book
Format: Paperback
I found this book on a recommended Early Math reading list posted on the PBS Parents website. Since there are no words in this book, there is nothing to actually read to your child. But it is likely one of the longest 12 page books I've read. And it is by far the most significant number book my 3 year old has read. Anno uses a town to depict and define numbers 0-12, the seasons, and the months of the year. The seasons and months are recognizeable, but not the focus like the numbers are. For the number 0, you see a blank landscape with a small river. When the child turns the page, he sees a large number 1 on the right side of the book and in the landscape one lone building, one tree, one sun, one snowman.... There is also a set of blocks on the left side of the book, with one block colored in. Thus, the child can see the number 1 represented as a numeral, as a block (of a set of 10), and as an object (one building, one tree, one person). As you turn the pages and the numbers increase, a village forms. The final page is the number 12 -- a full village at Christmas time, complete with 12 reindeer in the sky. As a parent, I enjoy having my daughter "read" to me. But I am most amazed by how the book has helped her to grasp the concept of numbers. As she explained, "0, Mommy. Because there's nothing there."
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Reviewed in the United States on March 1, 2009

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