SKU: 6327498560

GFAP Recombinant Rabbit mAb (SDT-1561-14)

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Description

GFAP Recombinant Rabbit mAb (SDT-1561-14)Product Specification Host Rabbit Antigen GFAP Synonyms Glial fibrillary acidic protein; GFAP Immunogen Recombinant Protein Accession P14136 Clone Number SDT 1561 14 Antibody Type Recombinant mAb Isotype IgG Application CLIA, Sandwich ELISA Reactivity Hu, Ms Cross Reactivity No cross reactivity against NFL, UCHL 1, Tau 441, S100B Purification Protein A Concentration 2 mg ml Purity >95% by HPLC Conjugation Unconjugated Physical Appearance Liquid

Product Specification


Host Rabbit
Antigen GFAP
Synonyms Glial fibrillary acidic protein; GFAP
Immunogen Recombinant Protein
Accession P14136
Clone Number SDT-1561-14
Antibody Type Recombinant mAb
Isotype IgG
Application CLIA, Sandwich ELISA
Reactivity Hu, Ms
Cross Reactivity

No cross-reactivity against NFL, UCHL-1, Tau-441, S100B
Purification Protein A
Concentration 2 mg/ml
Purity >95% by HPLC
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt, 2 to 8 °C as supplied

Background

Human glial fibrillary acidic protein (GFAP) is a 432-amino acid long polypeptide encoded by the corresponding gene on chromosome 17q21. It belongs to the type-III intermediate filaments and is responsible for maintaining the mechanical strength of astrocytes which support and regulate the blood-brain barrier. Moreover, GFAP is involved in fundamental and critical astrocytic functions like motility, proliferation, synaptic plasticity, myelination and responses to brain damage. GFAP is highly but not exclusively expressed in astrocytes in the central nervous system (CNS). GFAP has recently drawn attention due to its potential as a promising biomarker for several neurological disorders where it has been shown to have value in disease diagnosis as well as disease progression and treatment monitoring. Several studies have demonstrated elevated GFAP levels in Alzheimer’s disease (AD). Furthermore, blood GFAP levels seem to increase more than 10 years before symptom onset in genetic AD patients. In addition, blood GFAP levels might be able to predict the conversion from AD mild cognitive impairment to AD dementia. In multiple sclerosis (MS) GFAP levels vary by MS subtype and may be used as disease severity and progression biomarker.

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SKU: 6327498560

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4.7 ★★★★★
Based on 8 reviews
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Product Reviews
M
Verified Purchase
Matt K
Charlottesville, US
★★★★★ 3
There are better books out there
Format: Paperback
I knew so much of what I read that I stopped reading 2/3 into the book. This is an average book.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 4, 2022
A
Verified Purchase
Alex L.
Louisville, US
★★★★★ 5
Great book nice addition to howe library
Format: Paperback
The kid i bought it for loves it and rereads often. The paper is the nice shiny kind and colorful
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 13, 2025
K
Kindle Customer
Louisville, US
★★★★★ 5
Another glimpse of the boy-behind-the-bat, with humor and heart; 4.5 stars
Format: Kindle
1st Line: "This is Gotham City." Review: This new graphic novel, of a pre-Batman Bruce Wayne as a kid, opens in a Gotham City already all but decimated by crime and corruption. But with all its horrors, the worst of them for the young, rich, highly-intelligent but otherwise nerdy Bruce Wayne, orphaned after the murders of his parents, is none other than the Gotham Preparatory School for the Really, Really Gifted - his middle school. Here, all the students have some form of super power or another (The Flash, Wonder Woman, Superman, Penguin, Catwoman, and more - all started off in middle grade here) ... except for Bruce, who only got into the school because his parents funded the building of it before their deaths, and remains a target for bullies for not having any powers of his own. But when fellow student Jack Napier, himself having no super powers except for conning his way into the school, begins bullying Bruce's friend, elementary student Dick Grayson, Bruce becomes determined to strike back - thus beginning his ascent to a career as a vigilante, even as his loyal butler Alfred and the school's vice-principal forbid it. But will Bruce get it together in time to foil Jack's plans for the Crime of the Semester? And what of Bane, Jack's new sidekick, who would be a formidable foe even for someone with superpowers? Bruce Wayne: Not Super is terrific; a comedic look at the young, super-smart yet geeky Bruce completely out of his element as a young kid, formerly with the attention span of a goldfish, who may have finally found his calling. Also nice are the glimpses of a number of future DC superhero icons in their youth, but the story really does belong to the humor of Bruce wanting to save his city, agreeing to take a hyperactive Robin in tow as his sidekick, with no knowledge of how to fight and an arsenal of weapons thrown together in minutes - and potentially of harm more to the user than the bad guy - all while Alfred says no and remains in constant threat of sending the future Batman to his room. The poor kid, after all, can't even put a bat costume together; in it, he's mistaken for everything from a badger to a rat to even a prairie dog. Bruce pushes past it all, his pluck and determination to save Gotham City one villain at a time his true calling, and among writer Stuart Gibbs glib and funny humor and Berat Pekmezci's bursting-with-color art, the very basic but heartfelt beginnings of the boy who'd grow to become The Bat shines through. It's really good. So good, I already itch for a sequel. 4.5/5 stars
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 14, 2023
J
Verified Purchase
J. Dieterle
Los Angeles, US
★★★★★ 4
Fun story with familiar characters
Format: Paperback
4 stars = Great! Might re-read. This was fun! I enjoyed the illustrations and getting to scan the crowd scenes for more DC characters. I enjoyed Bruce's journey. I didn't love the portrayal of Clark Kent here, but the rest of this was fun. I would definitely read more of these if there are going to be sequels. There's a one-star review here that is completely on target in their assessment of some of the liberties taken in the book. Buyer/reader will have to decide if those observations will lead you to skip this one or if you can set aside those internal inconsistencies to accept the story as is.
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Reviewed in the United States on April 15, 2023
A
Avid Reader
Whiting, US
★★★★★ 5
Fun for kids and those kids at heart!
Format: Paperback
When I was a kid around 8 or 9 years old, we would go to an outdoor theatre, a special treat. I remember the old 1960's era Batman movies playing on the screen. It was fun, exciting, heroic...all those things that made it pure enjoyment. When I think of recent Batman movies that have turned dark, deadly, desperate, all the fun has gone out of those experiences and I simply don't watch those movies. This is simply a long way of saying that this book, Bruce Wayne: Not Super, brought back all the fun I experienced as a kid. Here we have our hero, who doesn't think he is, who compares himself to everyone around him with supernatural abilities, and begins to grow desperate. The background story is essentially the same: dead parents, rotten town, etc. But we see life from his perspective and can root for him all the way. He goofs up, makes lots of mistakes and this makes him even more lovable. This book is prefect for readers young and old, and if this made into a movie, I guarantee you that I would watch it. Highly recommended.
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Reviewed in the United States on April 4, 2024

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