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Description
Her3 His Tag Protein, MouseProduct Specification Species Mouse Synonyms Her3, ERBB3, LCCS2, MDA BF 1, MGC88033, c erbB3, erbB3 S, p180 ErbB3, p45 sErbB3, p85 sErbB3 Accession Q61526 Amino Acid Sequence Ser20 His641, with C terminal 10*His
Product Specification
| Species | Mouse |
| Synonyms | Her3, ERBB3, LCCS2, MDA-BF-1, MGC88033, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 |
| Accession | Q61526 |
| Amino Acid Sequence | Ser20-His641, with C-terminal 10*His SEMGNSQAVCPGTLNGLSVTGDADNQYQTLYKLYEKCEVVMGNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSVLPLPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLRFTQLTEILLGGVYIEKNDKLCHMDTIDWRDIVRVPDAEIVVKNNGGNCPPCHEVCKGRCWGPGPEDCQILTKTICAPQCNGRCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPAPLVYNKLTFQLEPNPHIKYQYGGVCVASCPHNFVVDQTFCVRACPADKMEVDKNGLKMCEPCRGLCPKACEGTGSGSRYQTVDSSNIDGFVNCTKILGNLDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRVYISANQQLCYHHSLNWTRLLRGPAEERLDIKYNRPLGECVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSREGVCVTHCNVLQGEPREFVHEAHCFSCHPECQPMEGTSTCNGSGSDACARCAHFRDGPHCVNSCPHGILGAKGPIYKYPDAQNECRPCHENCTQGCKGPELQDCLGQAEVLMSKPHGGGSGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 80-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Zhang N. et al. (2016) HER3/ErbB3, an emerging cancer therapeutic target. Acta Biochim Biophys Sin. 48(1): 39-48. |
Background
HER3 is a member of the HER (EGFR/ErbB) receptor family consisting of four closely related type 1 transmembrane receptors (EGFR, HER2, HER3, and HER4). HER receptors are part of a complex signaling network intertwined with the Ras/Raf/MAPK, PI3K/AKT, JAK/STAT, and PKC signaling pathways. Aberrant activation of the HER receptors and downstream signaling molecules tips the balance on cellular events, leading to various types of cancers. The HER3 protein is expressed in several types of tumors. That fact, together with the role of HER3 in promoting cell proliferation, implicate that targeting HER3 may have therapeutic relevance. Furthermore, expression and activation of HER3 has been linked to resistance to drugs that target other HER receptors such as agents that act on EGFR or HER2.
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4.2 ★★★★★
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Product Reviews
★★★★★ 4
Nice shelves
Color: Black, Size: 15.7 inch, Color: Black, Size: 15.7 inch
My son has a small bedroom & not a lot of storage, so I was looking for something to hold his cologne & hair products, etc. I know these are ‘bathroom shelves’, but the black went well with his room decor. They look great & are exactly what he needed. They were easy to install & seem stable. The only slightly negative thing is the quality of the shelf part. It’s a cheap mdf-type material & had a couple areas that had the black paint scratched off, but it was so minor I’m fine with it. They look nice & have an industrial look, which is great for a boys room.
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Reviewed in the United States on January 14, 2025
★★★★★ 5
Cute wall storage option
Color: Dark Brown, Size: 15.7 inch
Perfect addition to the bathroom and adds a little storage space for the extra rolls of toilet paper. Assembles in no time and install was easy.
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Reviewed in the United States on May 20, 2026
★★★★★ 5
Well made shelves
Color: Dark Brown, Size: 15.7 inch
Cute and easy to attach to the wall.
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Reviewed in the United States on March 31, 2026
★★★★★ 5
Must buy!
Color: Dark Brown, Size: 15.7 inch
Very nice and sturdy!
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Reviewed in the United States on May 7, 2026
★★★★★ 5
Stylish and Practical Storage Solution
Color: Black, Size: 15.7", Color: Black, Size: 15.7"
Love these floating shelves! They are sturdy, easy to install, and perfect for adding extra storage in the bathroom.
I used them over the toilet and they fit perfectly. They helped me organize essentials while also making the space look more modern and put together.
Great quality and very functional. Highly recommend for small bathroom upgrades!
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Reviewed in the United States on May 5, 2026