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Description
S-RMab®Annexin A2 Recombinant Rabbit mAb (SDT-444-67)Product Specification Host Rabbit Antigen Annexin A2 Synonyms Annexin II, Annexin 2, ANXA2, Calpactin I heavy chain, Calpactin 1 heavy chain, Chromobindin 8, Lipocortin II, Placental anticoagulant protein IV, PAP IV, Protein I, p36 Immunogen Recombinant Protein Location Secreted Accession P07355 Clone Number SDT 444 67 Antibody Type Recombinant mAb Application WB, IHC P, ICC Reactivity Hu Predicted Reactivity Ms, Pg, Dg Purification Protein A
Product Specification
| Host | Rabbit |
| Antigen | Annexin A2 |
| Synonyms | Annexin II, Annexin-2, ANXA2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV, PAP-IV, Protein I, p36 |
| Immunogen | Recombinant Protein |
| Location | Secreted |
| Accession | P07355 |
| Clone Number | SDT-444-67 |
| Antibody Type | Recombinant mAb |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu |
| Predicted Reactivity | Ms, Pg, Dg |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:5000 | |
| ICC | 1:50 |
Background
Annexin A2 is a membrane scaffolding and binding protein, which mediated various cellular events. Its functions are generally affected by cellular localization. In the cytoplasm, they interacted with different phospholipid membranes in Ca2+ -dependent manner and play vital roles including actin binding, remodeling and dynamics, cytoskeletal rearrangement, and lipid-raft microdomain formation. However, upon cell exposure to certain stimuli, annexin A2 translocates to the external leaflets of the plasma membrane where annexin A2 was recently reported to serve as a virus receptor, play an important role in the formation of virus replication complex, or implicated in virus assembly and budding [PMID: 30746844].
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