Pure Spermidine - 1 mg, 180 capsules

Spermidine - A Vital Compound for Cellular Repair and Longevity* 

• Replenish spermidine*¹
  
• Boost autophagy*^1-3
  
• Mimic the positive effects of fasting*²
  
• Optimize healthy aging*^1-5
  

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• Purely Sourced: Made from purified wheat germ extract, precisely standardized for maximum spermidine content.
  
• Never Synthetic: Formulated exclusively from natural sources to provide food-grade spermidine—free from synthetic spermidine trihydrochloride.
  
• Ideal Dosage: Each capsule delivers "the just right dose" of spermidine to support healthy autophagy activation.*^1-3
• Trusted Quality Since 1988: USA manufactured, 3rd-party lab tested, GMP certified for your peace of mind.

What Makes Ours Better?

• Longevity Focused: We leverage cutting-edge advancements in aging research to formulate products that address the fundamental causes of aging.*
  
• Triple Lab Tested: Every product is tested three times by independent 3rd-party labs to ensure we meet the highest standards.
  
• Complete Transparency: In an industry flooded with fake supplements, we stand apart by publishing our 3rd-party lab test results. We’re committed to showing you exactly what’s in every bottle, so you can feel confident in what you’re putting into your body.
  
• USA Manufacturing Excellence: Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards.*
  
• 100-Day Risk-Free Guarantee: We stand behind our products. Not satisfied? Reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions.

Spermidine is a naturally occurring polyamine compound present in all living organisms, derived from the amino acid ornithine. It plays a crucial role in youthful cellular processes and uniquely activates autophagy, the body’s cellular cleanup mechanism. Autophagy facilitates the breakdown and recycling of old and damaged cellular components, helping to rejuvenate cell structure and function.*^1-3

While fasting and caloric restriction are the most well-known methods for activating autophagy, supplementing with spermidine provides a groundbreaking alternative that mimics the benefits of fasting, effectively “turning on” autophagy without the need for caloric restriction.*^1-3

ProHealth Pure Spermidine offers a pure, vegan, and non-GMO source of this powerful compound, supporting the body’s natural cellular renewal processes. For best results, we recommend taking 1 to 3 capsules with your evening meal to jump-start an overnight fast or with breakfast to extend the benefits of your overnight fasting period.*²

Spermidine - A Vital Compound for Cellular Repair and Longevity*

Boost autophagy (cellular clean-up)*^1-3
Spermidine acts directly on our cells to restore them to a healthy state. It works by inducing autophagy - a process that keeps our cells working more efficiently by removing damaged parts of the cell and repairing cellular function.*^1-3

Mimic the positive effects of fasting*²
When we fast - extend the time between meals - spermidine levels increase, activating cellular repair and restoration processes that promote healthy aging. Supplementing with spermidine can mimic key aspects of the fasting state, allowing your body to experience its healthy aging benefits.*²

Optimize healthy aging*
Spermidine intake is associated with a healthy life span and may support up to nine hallmarks of aging. A research study showed that people who consume more spermidine are likely to live longer, compared to those who consume lower levels.  And research shows that supplementing with spermidine can help preserve the length of telomeres - the regions of DNA that shorten as you age.*^1,4

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Ingredients:

• Wheat germ extract: (Triticum aestivum): A concentrated food source of spermidine.
  

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

¹ Hofer et al. Nat Aging. 2022 Dec 22;2(12):1112-1129. 
² Hofer et al. Nat Cell Biol. 2024 Sep;26(9):1571-1584. 
³ Madeo et al. Autophagy. 2019 Jan;15(1):165–168. 
⁴ Kiechl et al. Am J Clin Nutr. 2018 Aug 1;108(2):371-380. 
⁵ Wirth et al. Geroscience. 2021 Apr;43(2):673-690.