SKU: 84542922427

Sirtuin 6 Activator - 60 capsules

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Description

Sirtuin 6 Activator - 60 capsulesSirtuin 6 Activator: Inspired by the Blue Zones Activates sirtuin 6 (SIRT6)1,4,6,7* Provides Blue Zone bioactives*5,6 Supports multiple longevity pathways*5 Neutralizes free radicals*5,12 Supports a healthy immune system & inflammatory response* 8,5,9 11 View Certificate of Analysis Not all fucoidan is created equal. After three years of extensive research and testing, we've finally sourced an authentic Fucus vesiculosusa special type of seaweed

Sirtuin 6 Activator: Inspired by the Blue Zones

  • Activates sirtuin 6 (SIRT6)1,4,6,7*
  • Provides “Blue Zone” bioactives*5,6
  • Supports multiple longevity pathways*5
  • Neutralizes free radicals*5,12
  • Supports a healthy immune system & inflammatory response* 8,5,9-11

View Certificate of Analysis

Not all fucoidan is created equal. After three years of extensive research and testing, we've finally sourced an authentic Fucus vesiculosus—a special type of seaweed renowned for its powerful fucoidan content and abundant marine polyphenols. This premium seaweed extract sets a new benchmark in longevity science.* 2,5,8,13,21,22,25

What Makes Ours Better?

  • Fucoidan-Rich Seaweed: We deliver pure, concentrated seaweed—not synthetic compounds or low-quality extracts—packed with fucoidan, a potent SIRT6 activator.*21,22
  • Longevity Boost: Each serving provides a full 400mg dose of fucoidan, the scientifically-backed compound for healthy aging.*
  • Full Spectrum Support: Our formula blends whole-plant seaweed powder with high-potency extracts, offering a more complete range of bioactive compounds to amplify fucoidan’s anti-aging potential.*12,15
  • Maximized Bioactivity: Unlike many seaweed extracts that lose potency through harsh processing, our fucoidan is gently extracted using a specialized water-based method, preserving its full molecular structure for optimal effectiveness.*5

Why Choose ProHealth?

  • Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*
  • Triple Lab Tested: Subjected to three rounds of independent third-party lab testing to ensure unmatched potency and purity.
  • Full Transparency: In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.
  • Manufactured in the USA: Made in FDA-regulated, GMP-certified facilities, adhering to the highest quality and safety standards.
  • 100-Day Risk-Free Guarantee: We’re confident you’ll love our product. If you’re not satisfied, contact our Santa Barbara, CA office for a full refund within 100 days—no hassle, no questions asked.

Not all fucoidan is created equal.

For centuries, Japan—home to one of the world’s longest-living populations—has relied on seaweed as a dietary staple, prized for its powerful antioxidants and cellular-protective compounds. Research consistently links regular seaweed consumption to enhanced health and longevity, reinforcing its vital role in healthy aging.*15

Building on this tradition, Sirtuin 6 Activator delivers fucoidan, one of seaweed’s most potent bioactive compounds. Naturally found in the cell walls of brown seaweed, fucoidan is clinically recognized for its ability to activate SIRT6, a key enzyme that supports healthy aging at the cellular level.*1


By activating SIRT6, this fucoidan-rich formula goes beyond simple antioxidant support to revitalize cellular health at its core. Research shows that increased SIRT6 activity can aid in DNA repair, boost genomic stability, and support a healthy systemic inflammatory response—processes linked to longevity in Blue Zone populations.*5,8,9,12,14,16

Emerging studies further suggest that higher SIRT6 activity correlates with longer lifespans in multiple animal species. Scientists are now exploring its potential for brain aging, heart health, and overall longevity, with human trials underway to further uncover its impact on healthy aging.*20,26-28


Sirtuin 6 Activator: Inspired by the Blue Zones

Aging is associated with cellular changes, including DNA damage, inflammation, and metabolic shifts, all of which have been studied in relation to SIRT6’s biological functions. Research suggests that SIRT6 plays a role in key cellular processes that support overall health.*

  • Supports DNA Repair – SIRT6 stabilizes the genome by repairing double-strand breaks and maintaining telomere integrity, reducing genetic instability, a major hallmark of aging.*6
  • Influences Metabolic Balance – SIRT6 shifts cells away from inefficient sugar metabolism and toward fat oxidation, mimicking the anti-aging effects of caloric restriction.*17
  • Clears Senescent Cells – Fucoidan acts as a potential senolytic, helping the body remove dysfunctional cells that drive aging.*4,13,19
  • Protects Mitochondria – SIRT6 supports healthy cellular energy production, safeguarding from oxidative stress so cells can generate energy efficiently.*5

Neutralizes Free Radicals*

Oxidative stress occurs when free radicals accumulate and damage cells, proteins, and DNA—a primary driver of aging. ProHealth Sirtuin 6 Activator combats oxidative damage through multiple pathways:

  • Directly Scavenges Free Radicals – Fucoidan’s unique sulfated polysaccharide structure binds to and neutralizes reactive oxygen species (ROS) before they can harm cells.*12
  • Provides Antioxidant Support – This formula combines fucoidan with polyphloroglucinols, marine polyphenols that strengthen cellular defenses against oxidative damage.*5
  • Enhances Cellular Antioxidant Pathways – By enhancing glutathione and superoxide dismutase (SOD) levels, SIRT6 supports the body’s natural ability to maintain oxidative homeostasis.*12

Supports a Healthy Immune System & Inflammatory Response*

Healthy immune system and inflammatory responses are essential for long-term health and longevity. Research suggests that fucoidan and SIRT6 may help support immune function and inflammation balance through multiple pathways:

  • Supports Immune Cell Activity – Fucoidan supports the activity of macrophages, natural killer (NK) cells, and lymphocytes, helping to maintain a robust immune system and clear damaged cells.*5,8,10
  • Helps Maintain a Healthy Inflammatory Response – SIRT6 influences cytokine activity and inflammatory response mechanisms, helping to support healthy inflammation for optimal aging.* 5,8,9
  • Enhances Gut-Immune Function – Fucoidan supports a healthy gut microbiome, which is closely linked to immune and inflammatory balance.*11

Order now and join the 200,000+ people who trust ProHealth Sirtuin 6 Activator for their cellular health!

Ingredients:

  • Brown Seaweed (Fucus vesiculosus): A rich source of fucoidan, a bioactive polysaccharide recognized for supporting cellular health and activating SIRT6, the longevity enzyme.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

  1. Rahnasto-Rilla M et al. Mar Drugs. 2017;15(6):190.
  2. Kawaguchi T et al. Int J Oncol. 2015;46(5):2216-2222.
  3. Yu W et al. Mol Nutr Food Res. 2017;61(10):1700136.
  4. Cao L et al. Mar Drugs. 2020;18(11):564.
  5. Li B et al. Molecules. 2008;13(8):1671-1695.
  6. López-Otín C et al. Cell. 2023;186(2):243-278.
  7. Iso H and Kubota Y. Asian Pac J Cancer Prev. 2007;8 Suppl:35-80.
  8. Jayawardena TU et al. Mar Drugs. 2022;20(12):755.
  9. Apostolova E et al. Polymers. 2020;12(10):2338.
  10. Bogolitsyn K et al. Plant Foods Hum Nutr. 2024;79(2):511-517.
  11. Luthuli S et al. Mar Drugs. 2019;17(9):487.
  12. Catarino MD et al. Mar Drugs. 2018;16(8):249.
  13. Zhang L et al. Innov Aging. 2022;6(Suppl 1):130.
  14. Myers S et al. Biol Targets Ther. 2011;45.
  15. Myers S. Biol Targets Ther. 2010;33.
  16. Li X et al. Front Cell Dev Biol. 2021;9:641315.
  17. Zhang N et al. Cell Cycle. 2016;15(7):1009-1018.
  18. Chilton WL et al. PLoS ONE. 2014;9(4):e92088.
  19. Akter R et al. Int J Mol Sci. 2021;22(8):4180.
  20. Zhang L et al. Innov Aging. 2022;6(Suppl 1):130.
  21. Gorbunova V. Innov Aging. 2019;3(Suppl 1):S8.
  22. Kawamura A et al. Mar Drugs. 2021;19(8):452.
  23. Willcox DC et al. Ann NY Acad Sci. 2009;1173:126-138.
  24. Buettner D. Natl Geogr Books. 2015.
  25. Korotkov A et al. Trends Cell Biol. 2021;31(12):994-1006.
  26. Zhang L et al. Oxid Med Cell Longev. 2019;2019:8918914.
  27. Yang J et al. Int J Biol Macromol. 2024;277(Pt 3):134397.
  28. Wang K et al. Ther Adv Chronic Dis. 2022;13:20406223221076891.
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Fucoidan (from Bladderwrack [Fucus vesiculosus] Whole Plant Extract and Brown Seaweed [Undaria pinnatifida] Whole Plant Extract) 400 mg
Bladderwrack (Fucus vesiculosus) Whole Plant Powder 100 mg
† Daily Value (DV) not established
REV.10.24

  • OTHER INGREDIENTS: Vegetable cellulose (capsule), microcrystalline cellulose, bamboo silica.
    • May contain traces of fish and/or shellfish residue.
  • SUGGESTED DAILY USE: Take one (1) capsule daily, or as directed by your healthcare professional.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 84542922427

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Amazon Customer
San Leandro, US
★★★★★ 5
Soft, lightweight golf shirt
Color: Turquoise, Size: Medium
I got this for my husband who occasionally golfs with work buddies as of recently. This golf shirt was perfect for him because it’s soft and the thinness helps with sweat and keeping it cool which is necessary where we live. The color is great and matches with most of his other shirts. It feels like a nice quality shirt while also being very lightweight. I’m sure if he was into wearing polos regularly, he would probably were it all the time. The size we got fit great and washing it was easy. Overall this is a great lightweight polo for being active.
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Reviewed in the United States on May 28, 2026
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Tung Nguyen
Waukegan, US
★★★★★ 4
It's more than golf shirt.
Color: Grey, Size: Large
This shirt is great for summer, beach, casual wear and outdoor activities. It's cool to touch and dry quick. The only thing you should be aware is that if you are on the plus size, the shirt does stick to your body sometimes and it does not compliment your body type well.
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Reviewed in the United States on April 24, 2026
J
Jqdlux
Battle Creek, US
★★★★★ 5
Soft and Easy Care
Color: Turquoise, Size: Medium, Color: Turquoise, Size: Medium
This is a great lightweight and moisture wicking golf shirt. The color is pretty and it has a UPF rating of 30+. The fabric has a soft, luxurious feel and the fit is true to size. The snaps fasten easily and are of good quality. This shirt washed up easily with no need for ironing. A nice shirt at a great price!
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Reviewed in the United States on May 18, 2026
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E
Bozeman, US
★★★★★ 3
Almost perfection
Color: Khaki, Size: XX-Large
I have really liked this polo the fit is great material is so lightweight and breathable Chef's kiss. the one thing i didn't like is the white accent parts are like heat applied and peeled off after 2 washes it doesn't do anything to the polo but still a little disappointing i just peeled the rest of them off so quality leaves a little bit to be desired there. i wish they didn't include them and it would be 5/5 for me but if after 4 or 5 wears and 2 washes it peels off that is a little disappointing
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Reviewed in the United States on May 17, 2026
D
Devan
Whiting, US
★★★★★ 5
This Shirt Is So Cozy My Husband Loves It — Perfect Fit and Style!
Color: Turquoise, Size: X-Large
I recently picked up the Alex Vando Men’s Golf Shirt, and I have to say, it has quickly become one of my husband’s favorites in his wardrobe. From the moment he tried it on, he raved about how soft and comfortable it feels. The material is lightweight and breathable, yet it doesn’t feel flimsy — it strikes the perfect balance for both everyday wear and active use. The moisture-wicking and quick-dry properties are a game-changer. He’s worn it for golf, casual outings, and even on warmer days, and it keeps him cool and dry without sticking uncomfortably. The UPF30+ is an added bonus for sunny days outside, giving some extra peace of mind during golf or tennis sessions. What I really love — and what he notices — is the attention to detail. The 3D checkered texture gives the shirt a subtle, sophisticated look that feels premium. The color-matched snap buttons are secure and easy to use, and the fine line detailing along the placket adds a touch of depth. The side panels and slit hem make movement easy, so he doesn’t feel restricted during activities. It’s clear this shirt is designed with both style and performance in mind. Fit-wise, it’s fantastic. It flatters his physique without feeling tight, giving a clean, streamlined look. He’s worn other golf polos before that were either too stiff or too loose, but this one hits the sweet spot perfectly. Another huge plus is the practicality. This shirt is wrinkle-resistant and washes beautifully, requiring no ironing. That makes it perfect for busy days when he wants to look sharp without extra effort. Overall, the Alex Vando Men’s Golf Shirt is a winner. It’s stylish enough for business casual, functional enough for sports, and incredibly comfortable for everyday wear. My husband loves it, and I’ve already noticed him reaching for it again and again. If you’re looking for a high-quality, versatile polo that combines comfort, style, and performance, this is absolutely worth trying.
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